(2S)-2,6-diaminohexanoic acid
glatiramer acetate
CAS: 147245-92-9
Molecular Formula: C25H45N5O13
(2S)-2,6-diaminohexanoic acid - Names and Identifiers
| Name | glatiramer acetate |
| Synonyms | ProtiraMer glatiramer acetate GaltiraMer acetate GLATIRAMER ACETATE (2S)-2-aminopropanoic acid (2S)-2,6-diaminohexanoic acid (2S)-2-aminopentanedioic acid acetic acid, (2S)-2-amino-3-(4-hydroxyphenyl)propanoic acid L-Alanine polyMer with L-GlutaMic Acid L-Lysine L-Tyrosine Acetate L-Tyrosine polyMer with L-Alanine L-GlutaMic Acid L-Lysine Acetate L-GlutaMic Acid peptide with L-Alanine L-Lysine L-Tyrosine Acetate Salt l-glutamic acid polymer with l-alanine, l-lysine and l-tyrosine, acetate (salt) |
| CAS | 147245-92-9 |
| EINECS | 814-981-5 |
| InChI | InChI=1/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2.C2H4O2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6;1-2(3)4/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6);1H3,(H,3,4)/t8-;5-;3-;2-;/m0000./s1 |
(2S)-2,6-diaminohexanoic acid - Physico-chemical Properties
| Molecular Formula | C25H45N5O13 |
| Molar Mass | 623.66 |
| Melting Point | >239°C (dec.) |
| Boling Point | 385.2°C at 760 mmHg |
| Flash Point | 186.7°C |
| Solubility | Methanol (Slightly), Water (Slightly) |
| Vapor Presure | 1.27E-06mmHg at 25°C |
| Appearance | Solid |
| Color | White to Off-White |
| Storage Condition | Refrigerator |
| In vitro study | Glatiramer acetate (25-100 mg/kg; S.c; 5 days) increase BDNF levels. In huntington’s disease (HD) mouse model, the N171-82Q transgenic mouse line, which exhibits a more rapidly progressing disease course. Glatiramer acetate (1 mg/mouse; s.c.; 5×week) beginning at 8 weeks of age and continuing until 20 weeks of age, which is near the age of death due to the disease. Glatiramer acetate elicited improves performance on several motor function measures. Glatiramer acetate significantly improves the performance of N171-82Q transgenic mice at 15 weeks of age in the rotarod test measured over the course of 4 days. |
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CAS: 147245-92-9
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CAS: 147245-92-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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